Medizinische Universitätsklinik Bochum

www.medunikkh.de

Publikationen

Arbeiten

191. Kaltz B, Bokemeyer B, Hoffmann J, Porschen R, Rogler G, Schmiegel W. Überwachungskoloskopie bei Colitis ulcerosa in Deutschland. Z Gastroenterol 2007; 45: 325 - 331
190. Graeven U, Arnold D, Reinacher-Schick A, Heuer Th, Nusch A, Porschen R, Schmiegel W. A Randomised Phase II Study of Irinotecan in Combination with 5-FU/FA Compared with Irinotecan Alone as Second-Line Tretment of Patients with Metastatic Colorectal Carcinoma. Onkologie 2007;30:169-174
189. Ritzel RA, Kleine N, Holst JJ, Willms B, Schmiegel W, Nauck MA. Preserved GLP-1 Effects in a Diabetic Patient with Cushing’s Disease. ESP Clin Endocrinol Diabetes 2007; 115 :146-150
188. Diehl HC, Stuhler K, Klein-Scory S, Volmer, MW, Schoneck A, Bieling C, Schmiegel W, Meyer HE, Schwarte-Waldhoff I. A catalogue of proteins released by colorectal cancer cells in vitro as an alternative source for biomarker discovery. Proteomics Clin. Appl. 2007, 1, 47-61
187. Pox C, Schmiegel W, Classen M. Current status of screening colonoscopy in Europe and in the United States. Endoscopy. 2007 Feb; 39 (2): 168-73
186. Brechmann T, Massenkeil G, Schmiegel W. In Process Citation. Med Klin (Munich). 2007 Feb 15; 102 (2): 168-9
185. Ritzel RA, Kleine N, Holst JJ, Willms B, Schmiegel W, Nauck MA. Preserved GLP-1 Effects in a Diabetic Patient with Cushing’s Disease. Exp Clin Endocrinol Diabetes. 2007 Feb; 115 (2): 146-50
184. Basrai D, Pox C, Schmiegel W. Fever of intermediate duration after return from the Canary Islands. Internist (Berl). 2007 Feb 17
183. Nauck MA, Reinecke M, Perren A, Frystyk J, Berishvili G, Zwimpfer C, Figge AM, Flyvbjerg A, Lankisch PG, Blum WF, Kloppel G, Schmiegel W, Zapf J. Hypoglycemia due to paraneoplastic Secretion of Insulin-like Growth Factor-I in a Patient with Metastasizing Large-Cell Carcinoma of the Lung. J Clin Endocrinol Metab. 2007 Feb 13
182. Stuhler K, Koper K, Pfeiffer K, Tagariello A, Souquet M, Schwarte-Waldhoff I, Hahn SA, Schmiegel W, Meyer HE. Differential proteome analysis of colon carcinoma cell line SW480 after reconstitution of the tumour suppressor Smad4. Anal Bioanal Chem. 2006 Nov; 386 (6): 1603-12.
181. Zapatka M, Zboralski D, Radacz Y, Bockmann M, Arnold C, Schoneck A, Hoppe S, Tannapfel A, Schmiegel W, Simon-Assmann R, Schwarte-Waldhoff I. Basement membrane component laminin-5 is a target of the tumor suppressor Smad4. Oncogene. 1007 Mar 1; 26 (10): 1417-27

Arbeiten

Heringlake S, W. Schmiegel. Leberzirrhose. In: Lehrbuch Innere Medizin, Elsevier Verlag 2007.

Originalarbeiten in Peer-Reviewed Journals

1.Frank B, Burwinkel B, Bermejo JL, Försti A, Hemminki K, Houlston R, Mangold E, Rahner N, Friedl W, Friedrichs N, Buettner R, Engel C, Loeffler M, Holinski-Feder E, Morak M, Keller G, Schackert HK, Krüger S, Goecke T, Moeslein G, Kloor M, Gebert J, Kunstmann E, Schulmann K, Rüschoff J, Propping P; German HNPCC Consortium. Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families. Cancer Lett. 2008 Nov 18;271(1):153-7. Epub 2008 Jul 10.

2.Schulmann K, Engel C, Propping P, Schmiegel W. Small bowel cancer risk in Lynch syndrome. Gut. 2008 Nov;57(11):1629-30. Epub 2008 Mar 26.

3.Müller CI, Schulmann K, Reinacher-Schick A, Andre N, Arnold D, Tannapfel A, Arkenau H, Hahn SA, Schmoll SH, Porschen R, Schmiegel W, Graeven U. Predictive and prognostic value of microsatellite instability in patients with advanced colorectal cancer treated with a fluoropyrimidine and oxaliplatin containing first-line chemotherapy. A report of the AIO Colorectal Study Group. Int J Colorectal Dis. 2008 Nov;23(11):1033-9. Epub 2008 Jul 2.

4.Morak M, Schackert HK, Rahner N, Betz B, Ebert M, Walldorf C, Royer-Pokora B, Schulmann K, von Knebel-Doeberitz M, Dietmaier W, Keller G, Kerker B, Leitner G, Holinski-Feder E. Further evidence for heritability of an epimutation in one of 12 cases with MLH1 promoter methylation in blood cells clinically displaying HNPCC. Eur J Hum Genet. 2008 Jul;16(7):804-11. Epub 2008 Feb 27.

5.Müller A, Zielinski D, Friedrichs N, Oberschmid B, Merkelbach-Bruse S, Schackert HK, Linnebacher M, von Knebel Doeberitz M, Büttner R, Rüschoff J; German HNPCC Consortium, German Cancer Aid Deutsche Krebshilfe. Reduced mRNA expression in paraffin-embedded tissue identifies MLH1- and MSH2-deficient colorectal tumours and potential mutation carriers. Virchows Arch. 2008 Jul;453(1):9-16. Epub 2008 Jun 26.

6.Sato F, Jin Z, Schulmann K, Wang J, Greenwald BD, Ito T, Kan T, Hamilton JP, Yang J, Paun B, David S, Olaru A, Cheng Y, Mori Y, Abraham JM, Yfantis HG, Wu TT, Fredericksen MB, Wang KK, Canto M, Romero Y, Feng Z, Meltzer SJ. Three-tiered risk stratification model to predict progression in Barrett's esophagus using epigenetic and clinical features. PLoS ONE. 2008 Apr 2;3(4):e1890.

7.Selaru FM, Wang S, Yin J, Schulmann K, Xu Y, Mori Y, Olaru AV, Sato F, Hamilton JP, Abraham JM, Schneider P, Greenwald BD, Brabender J, Meltzer SJ. Beyond Field Effect: Analysis of Shrunken Centroids in Normal Esophageal Epithelia Detects Concomitant Esophageal Adenocarcinoma. Bioinform Biol Insights. 2007;1:127-136.

Proteomics Clinical Applications 2007, 1, 47-61

Diehl, H.C., Stühler, K., Klein-Scory, S., Volmer, M.W., Schöneck, A., Bieling, C., Schmiegel, W., Meyer, H.E., Schwarte-Waldhoff, I.
A catalogue of proteins released by colorectal cancer cells in vitro as an alternative source for biomarker discovery.
Proteomics Clinical Applications 2007, 1, 47-61